Similar to our previous blog posts covering the AABB abstracts from Vancouver General Hospital and The University of Colorado Hospital, this post presents an abstract generated by a hospital that recently completed a study using ThromboLUX.
This time we are looking at work done by Dr. Gerda Leitner and her team at the Vienna General Hospital. Their study aimed to understand the platelet activation status of plateletpheresis donors and whether the platelet activation status changed with repeat donations and processing.
Poster Number NIT25:
Understanding the Platelet Activation Status of Plateletpheresis Donors to Optimize Platelet Allocation
Platelet microparticles are known indicators of platelet activation. What is not known is if platelet activation is associated with certain donor demographics, or whether it is consistent for repeat donors. In this abstract, Dr. Leitner investigated the platelet activation status of 189 donors. Samples from the donors’ platelet-rich plasma and from their corresponding plateletpheresis products were tested.
Dr. Leitner and her team found that platelet activation status varied significantly between donors, but neither donor age nor sex predicts platelet activation status. Furthermore, donor platelet activation status remained largely consistent for up to three months but changed over longer time periods for many of the donors. One finding of interest was the statistically significant difference found between platelet products collected on Trima Accel and Amicus, where the latter contained more microparticles — thus indicating a higher degree of platelet activation.
For additional details on this study visit poster NIT25 on Sunday October 14, 2018 from 1:00 – 2:00 pm in the Boston Exhibition & Convention Center (BCEC) Hall A.
You can also hear about the results from four other ThromboLUX studies by attending our workshop at AABB the morning of October 15th, or by visiting us in the exhibit hall at Booth 724.